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KMID : 1037520160320040166
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Vascular Specialist International
2016 Volume.32 No. 4 p.166 ~ p.174
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Deep Vein Thrombosis in Patients with Pulmonary Embolism: Prevalance, Clinical Significance and Outcome
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Lee Jun-Sung
Moon Tong
Kim Tae-Hoon
Kim Se-Young
Choi Jun-Young
Lee Kyung-Bok
Kwon Yu-Jin
Song Suk-Hee
Kim Su-Hyun
Kim Hae-Ok
Hwang Ho-Kyeong
Kim Min-Ji
Lee Young-Kyoung
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Abstract
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Purpose: Deep venous thrombosis (DVT) and pulmonary embolism (PE) are considered as similar disease entities representing different clinical manifestations. The objectives of this study were: 1) to determine the prevalence and outcome of DVT in patients with PE; 2) to identify additional risk factors for PE-related unfavorable outcome and 30-day all-cause mortality; and 3) to establish the clinical importance of screening for concomitant DVT.
Materials and Methods: From January 2013 to December 2015, a total of 141 patients with confirmed PE were evaluated. The prevalence and outcome of DVT in patients with PE was determined. Furthermore, the potential risk factors for PE-related unfavorable outcome and 30-day all-cause mortality were also analyzed.
Results: The prevalence of concomitant DVT was 45.4%. PE-related unfavorable outcome was observed in 21.9% of all concomitant DVT, with all-cause mortality of 21.9%. There was no significant relationship between the presence of concomitant DVT and the development of PE-related unfavorable outcome or all-cause mortality. Our results indicated that heart rate >100/min and peripheral oxygen saturation <90% were independent predictors for PE-related unfavorable outcome. Regarding all-cause mortality, active malignancy and hypotension or shock were significant risk factors.
Conclusion: Our findings demonstrate that approximately half of patients with PE possess DVT. However, this study failed to establish any clinical significance of concomitant DVT for PE-related unfavorable outcome and all-cause mortality. Tachycardia and hypoxemia were identified as significant predictors for PE-related unfavorable outcome along with active malignancy and hypotension or shock as significant risk factors of all-cause mortality.
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KEYWORD
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Venous thrombosis, Pulmonary embolism, Prevalence, Outcome, Risk factors
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